大学MOOC 细胞生物学(西北农林科技大学)1450180232 最新慕课完整章节测试答案

BiomembraneStructure-test

1、单选题：
All the following statements describe biomembranes except:‍‍‍
选项：
A: Different biomembranes may contain different proportions of the same phospholipids.
B:  The two leaflets of a biomembrane may contain different phospholipids.
C:  Some biomembranes have free edges.
D: Some phospholipids and cholesterol may cluster to form lipid rafts.  
答案: 【  Some biomembranes have free edges.】

2、单选题：
‌ The major site of lipid synthesis in eukaryotic cells is the​
选项：
A: Nucleus
B: Endoplasmic reticulum
C: Mitochondria
D: Cell membrane
答案: 【 Endoplasmic reticulum】

3、单选题：
Phospholipids with short or unsaturated fatty acyl chains‌‌
选项：
A: decrease membrane fluidity.
B: increase membrane fluidity.
C:  cause biomembranes to become thicker
D: allow hydrophilic molecules to diffuse across the lipid bilayer.
答案: 【 increase membrane fluidity.】

4、单选题：
 The _______ are transmembrane proteins.‏‏
选项：
A: lipid-anchored membrane proteins
B: integral membrane proteins
C: peripheral membrane proteins
D: extracellular matrix proteins
答案: 【 integral membrane proteins】

5、单选题：
Glycolipids and glycoproteins are especially abundant in the‏
选项：
A:  nucleus.
B: mitochondrial inner membrane
C: cytosol
D: plasma membrane
答案: 【 plasma membrane】

6、单选题：
Phosphate containing lipids include all of the following except ‏
选项：
A:  phospholipids.
B: sphingolipid
C: triglyceride
D: phosphatidylinositol
答案: 【 triglyceride】

7、判断题：
‍A lipid bilayer is the fundamental structural component of all cell membranes.​‍​
选项：
A: 正确
B: 错误
答案: 【 正确】

8、判断题：
‎Maintenance of the lipid bilayer in the plasma membrane requires special enzymes and the hydrolysis of ATP.‌‎‌
选项：
A: 正确
B: 错误
答案: 【 错误】

9、填空题：
‍The most abundant lipids in cell membranes are ________________.‍‍‍
答案: 【 phospholipids】

10、填空题：
‌Sugar-containing lipids called ____________ are found only in the outer half of the bilayer and their sugar groups are exposed ac the cell surface.‏‌‏
答案: 【 glycolipids】

CellorganizationandmovementIIMicrotubulesandintermediatefilamen

1、单选题：
‏A microtubule protofilament is formed by the‍
选项：
A: a. lateral association of only g-tubulin subunits.
B: b. head-to-tail association of only g-tubulin subunits
C: c. lateral association of tubulin dimers.
D: d. head-to-tail association of tubulin dimers.
答案: 【 d. head-to-tail association of tubulin dimers.】

2、单选题：
‍ Growing microtubule ends are normally stabilized by  ‍‍
选项：
A: d. g-tubulin.
B: a. a GDP cap.
C: c. phosphorylation of tubulin subunits.
D: b. a GTP cap.
答案: 【 b. a GTP cap.】

3、单选题：
All of the following statements describe Kinesin I except‏‏
选项：
A: a. Kinesin I is a (−) end-directed motor.
B: b. Kinesin I transports vesicles along microtubules.
C: c. Kinesin I binds and hydrolyzes ATP to produce movement.
D: d. Kinesin I is composed of two heavy chains and two light chains.
答案: 【 a. Kinesin I is a (−) end-directed motor.】

4、单选题：
14. The force for axoneme bending is derived from the​​
选项：
A: a. sliding movement of central pair microtubules.
B: b. contraction of central pair microtubules.
C: c. sliding movement of outer doublet microtubules.
D: d. contraction of outer doublet microtubules.
答案: 【 c. sliding movement of outer doublet microtubules.】

5、单选题：
 The primary cilium‍‍‍
选项：
A: a. is non-motile because it lacks the “central pair” of microtubules.
B: b. is relatively susceptible to microtubule destabilizing drugs like colchicine.
C: c. has no known role in humans.
D: d. none of the above
答案: 【 a. is non-motile because it lacks the “central pair” of microtubules.】

6、单选题：
 ‍Poleward movement of chromosomes during anaphase A require‍‍
选项：
A: a. microtubule polymerization.
B: b. ATP.
C: c. kinetochore motor proteins.
D: d. BimC.
答案: 【 c. kinetochore motor proteins.】

CellorganizationandmovementIMicrofilament

1、单选题：
Within an actin filament, each actin subunit is surrounded by _______ neighboring actin subunits‌
选项：
A: a. one
B: b. two
C: c. four
D: d. eight
答案: 【 c. four】

2、单选题：
During treadmilling, actin subunits ad‌
选项：
A: a. predominantly to filament (+) ends.
B: b. predominantly to filament (−) ends.
C: c. equally to both filament ends.
D: d. along the length of filaments.
答案: 【 a. predominantly to filament (+) ends.】

3、单选题：
 Listeria is a bacteria parasite that has evolved unique ways to enter animal cells and then use actin polymerization for its intracellular movement.  Which of the following statements is true in regards to Listeria and actin polymerization?‍
选项：
A: a. Listeria ActA protein binds and inactivates the Arp2/3 complex.
B: b. Listeria ActA binds VASP, which enhances ATP-actin assembly.
C: c. Cofilin is necessary to accelerate the assembly of the (−) end of the filament.
D: d. CapZ promotes the elongation of the filament.
答案: 【 b. Listeria ActA binds VASP, which enhances ATP-actin assembly.】

4、单选题：
 ‍Which of the following properties is not shared by all myosins?‍
选项：
A: a. the ability to bind ATP
B: d. the presence of a head domain
C: b. the ability to form dimers
D: c. the ability to bind actin
答案: 【 b. the ability to form dimers】

5、单选题：
What is the function of CapZ and tropomodulin in the sacromere?‍
选项：
A: a. to center myosin thick filaments
B: b. to attach actin thin filaments to the Z disk
C: c. to maintain a constant actin thin filament length
D: d. to make contraction sensitive to Ca2+ 
答案: 【 c. to maintain a constant actin thin filament length】

6、单选题：
Gelsolin is activatikred by‍
选项：
A: a. ATP-binding.
B: d. dephosphorylation.
C: c. Ca2+-binding.
D: b. phosphorylation.
答案: 【 c. Ca2+-binding.】

7、单选题：
13. Which region of myosin interacts with actin filaments?​
选项：
A: a. the head domain
B: b. the rod domain
C: c. the light chains
D: d. the tail domain
答案: 【 a. the head domain】

8、单选题：
Which of the following proteins is involved in formation of actin bundles in microvilli by providing crosslinks between actin filaments‏
选项：
A: a. a actinin
B: b. cofilin
C: c. fimbrin
D: d. profilin
答案: 【 c. fimbrin】

CellularEnergetics

1、单选题：
‏Where does glycolysis takes place?‏
选项：
A: Mitochondrial matrix
B: Cytosol
C: Mitochondrial intermembrane space
D: Mitochondrial inner membrane
E: Mitochondrial outer membrane
答案: 【 Cytosol】

2、单选题：
‍Where is the electron transport chain found in plant cells?‏
选项：
A: Stroma of chloroplasts
B: Inner membrane of mitochondria
C: Thylakoid membranes of chloroplasts
D: Cytoplasm
答案: 【 Thylakoid membranes of chloroplasts】

3、单选题：
‏Energy released by the electron transport chain is used to pump H+ ions into which location?‍
选项：
A: Mitochondrial matrix
B: Mitochondrial intermembrane space
C: Mitochondrial inner membrane
D: Cytosol
答案: 【 Mitochondrial intermembrane space】

4、单选题：
​Inside an active mitochondrion, most electrons follow which pathway?​
选项：
A: Glycolysis --> NADH --> oxidative phosphorylation --> ATP --> oxygen
B: Citric acid cycle --> FADH2 --> electron transport chain --> ATP
C: Pyruvate --> citric acid cycle --> ATP --> NADH --> oxygen
D: Citric acid cycle --> NADH --> electron transport chain --> oxygen
答案: 【 Citric acid cycle --> NADH --> electron transport chain --> oxygen】

5、单选题：
‌Which do the catabolic products of fatty acid breakdown enter into the citric acid cycle?‍
选项：
A: Pyruvate
B: Acetyl CoA
C: Succinyl CoA
D: Malate or fumarate
答案: 【 Acetyl CoA】

6、单选题：
‌Brown-fat mitochondria uncouple oxidative phosphorylation to produce__________‏
选项：
A: ADP
B: Fat
C: Heat
D: Oxygen
答案: 【 Heat】

7、判断题：
‌During ATP synthesis, protons move “down” their electrochemical gradient through  the F0 complex of ATP synthase‏
选项：
A: 正确
B: 错误
答案: 【 正确】

8、判断题：
‏The outer mitochondrial membrane is derived from the bacterial plasma membrane‏
选项：
A: 正确
B: 错误
答案: 【 错误】

9、填空题：
‌__________ is a lipid soluble molecule that acts to shuttle electrons within the mitochondrial inner membrane​
答案: 【 CoQ】

10、填空题：
‎The energy released by the passage of electrons along the respiratory chain is stored as an___________ across the inner mitochondrial membrane.‏
答案: 【 proton motive force】

Culturingandvisualizingcells-test

1、单选题：
 The most direct source of monoclonal antibodies are ________ cells.​‎​
选项：
A: B lymphocytes
B: T lymphocytes
C: myeloma
D: Hybridoma
答案: 【 Hybridoma】