大学MOOC Pharmaceutics(China Medical University)1461326168 最新慕课完整章节测试答案
Basic Theories of Pharmaceutics & Liquid Pharmaceutical Preparations (1)
文章目录
1.1 Solubility of Drugs
1、多选题：
Which of the factors can affect the solubility of drug?
选项：
A: Molecular structure
B: Particle size
C: Dissolution temperature
D: Additive ingredient
答案: 【 Molecular structure;
Particle size;
Dissolution temperature;
Additive ingredient】
2、判断题：
If drug dissolution is an endothermic process, drug solubility will increase with increasing temperature.
选项：
A: 正确
B: 错误
答案: 【 正确】
1.2 Dissolution Rate of Drugs
1、多选题：
Which of the factors can affect the dissolution rate of drug?
选项：
A: Diffusion coefficient
B: Temperature
C: Properties of dissolution medium
D: Volume of dissolution medium
答案: 【 Diffusion coefficient;
Temperature;
Properties of dissolution medium;
Volume of dissolution medium 】
2、判断题：
According to the Nernst-Brunner Equation, the smaller the particle size of drug, the slower the dissolution rate of drug.
选项：
A: 正确
B: 错误
答案: 【 错误】
Basic Theories of Pharmaceutics & Liquid Pharmaceutical Preparations (1)
1、单选题：
Sodium dodecyl sulfate is
选项：
A: Anionic surfactant
B: Cationic surfactant
C: Zwitterionic surfactant
D: None of the above
答案: 【 Anionic surfactant】
2、单选题：
Which of the following are zwitterionic surfactants
选项：
A: Soaps
B: Fatty acid glycerides
C: Quaternary ammonium salts
D: Globulins
答案: 【 Globulins】
3、单选题：
Which of the following surfactants can be used as disinfectants
选项：
A: Benzalkonium bromide
B: Sodium dodecyl sulfate
C: Myrjs
D: Brijs
答案: 【 Benzalkonium bromide】
4、单选题：
Which of the following are non-ionic surfactants
选项：
A: Soft phospholipid
B: Tween 80
C: Sodium dodecyl sulfate
D: Benzalkonium chloride
答案: 【 Tween 80】
5、单选题：
The optimal range of HLB value required for solubilization is
选项：
A: 8 to18
B: 6 to 8
C: 15 to 18
D: 8 to 10
答案: 【 15 to 18】
6、单选题：
Which of the following is the most toxic surfactants
选项：
A: Tween 80
B: Soaps
C: Span 20
D: Benzalkonium bromide
答案: 【 Benzalkonium bromide】
7、单选题：
Which of the following can function as a W/O type emulsifier
选项：
A: Mrij 45
B: Acacia gum
C: Span 80
D: Tween 80
答案: 【 Span 80】
8、单选题：
According to DLVO theory, the main factor for the relative stability of sol is
选项：
A: The electric layer structure on the surface of colloidal particles
B: The colloidal particles and dispersion medium generate 5 potentials when moving far
C: Brownian motion makes colloidal particles difficult to coalesce
D: The electric repulsion generated when the ion atmosphere overlaps is dominant
答案: 【 The electric repulsion generated when the ion atmosphere overlaps is dominant】
9、单选题：
Which of the following statement about the optical properties of particles is incorrect
选项：
A: Light in solution of low molecular is mainly reflection
B: The reflection and scattering of light mainly depend on the size of the particles
C: Tyndall phenomenon is the macroscopic expression of particles reflecting light
D: Coarse dispersion system mainly makes light scattered
答案: 【 Light in solution of low molecular is mainly reflection】
10、单选题：
What kind of fluid glycerin belongs to
选项：
A: Swelling fluid
B: Thixotropic fluid
C: Newtonian fluid
D: Pseudoplastic fluid
答案: 【 Thixotropic fluid】
11、单选题：
Which of the following is non-polar solvent
选项：
A: Propylene glycol
B: Polyethylene glycol
C: Liquid paraffin
D: Glycerin
答案: 【 Liquid paraffin】
12、单选题：
Which of the following methods cannot increase the solubility of drugs
选项：
A: Adding cosolvent
B: Adding suspending agent
C: Transforming the drug to its salt form
D: Using cosolvent
答案: 【 Adding suspending agent】
13、判断题：
A drug is more soluble that keep at an amorphous state.
选项：
A: 正确
B: 错误
答案: 【 正确】
14、判断题：
According to the Nernst-Brunner Equation, the larger the thickness of diffusion layer, the slower the dissolution rate.
选项：
A: 正确
B: 错误
答案: 【 正确】
15、判断题：
The drug particle dispersion system is a kinetic stable but thermodynamically unstable system
选项：
A: 正确
B: 错误
答案: 【 错误】
Course test 1.3
1、单选题：
The structural characteristics of surfactant molecules are
选项：
A: with an ester bond
B: with an alcoholic hydroxyl structure
C: with both hydrophilic and lipophilic groups
D: with an ether bond
答案: 【 with both hydrophilic and lipophilic groups】
2、单选题：
Which of the following are anionic surfactants
选项：
A: Sodium cetyl sulfate
B: Poloxamer188
C: Span 65
D: Sucrose fatty acid ester
答案: 【 Sodium cetyl sulfate】
3、单选题：
When adding a large amount of calcium ion or magnesium ion, or the other multivalent cation to the anionic surfactant solution, what phenomenon may occur?
选项：
A: Precipitation
B: Flocculation
C: Solubilization
D: Clouding
答案: 【 Precipitation】
4、单选题：
Which of the following are cationic surfactants
选项：
A: Soaps
B: Sulfonates
C: Sulfates
D: Benzalkonium bromide
答案: 【 Benzalkonium bromide】
Course test 1.4
1、单选题：
Which of the following surfactants are those with a cloud point?
选项：
A: Sulfates
B: Soaps
C: Fatty acids sorbitans
D: Polysorbates
答案: 【 Polysorbates】
2、单选题：
The best range of HLB value for O/W emulsifier is
选项：
A: 6 to 9
B: 3 to 20
C: 8 to16
D: 3 to 8
答案: 【 8 to16】
3、单选题：
Which of the following statement is correct
选项：
A: Since Tween surfactants have little irritation to the skin and mucous membranes, they can be used in large doses for a long time
B: Surfactants may either promote the absorption of drugs or reduce the absorption of drugs
C: Anionic surfactant and cationic surfactant cannot be used together
D: Surfactant also has better solubilizing effect on dissociative drugs
答案: 【 Anionic surfactant and cationic surfactant cannot be used together】
4、单选题：
The property closely related to surfactant solubilization is
选项：
A: Surface activity
B: Formation of micelles in solution
C: Cloud point
D: HLB
答案: 【 Formation of micelles in solution】
Course test 1.5
1、单选题：
The particle size range of the particle dispersion system refers
选项：
A: Less than 1 nm
B: Between 1 and 100 nm.
C: Greater than 100 nm
D: Between 1 nm and 100 μm
答案: 【 Between 1 and 100 nm.】
2、判断题：
The charge on the surface of the particles can be neutralize by adding some electrolyte to the particle dispersion system. By doing this, the repulsion between the particles can be weakened due to the reduction of thickness of the electric bilayer.
选项：
A: 正确
B: 错误
答案: 【 正确】
Course test 1.6
1、单选题：
The nature of an object returning to its original state when its stress is removed is
选项：
A: Viscoelasticity
B: Plasticity
C: Elasticity
D: Swelling
答案: 【 Elasticity】
2、单选题：
Which of the following units is the one suitable for viscosity
选项：
A: N
B: N/m
C: Pa
D: Pa·s
答案: 【 Pa·s】
3、单选题：
Which of the following liquids is Newtonian fluid
选项：
A: Polymer solution
B: Colloid solution
C: Paclitaxel emulsion
D: Bacterial oil
答案: 【 Bacterial oil】
4、单选题：
As the shear rate increases, the fluid whose apparent viscosity increases is
选项：
A: Newtonian fluid
B: Plastic fluid
C: Swelling fluid
D: Thixotropic fluid
答案: 【 Thixotropic fluid】
Course test 2.1
1、单选题：
Which of the following is not a common additive for liquid preparations
选项：
A: Oxidizing agent
B: Preservative
C: Flavoring agent
D: Antioxidant
答案: 【 Oxidizing agent】
2、单选题：
The function of potassium iodide in the compound iodine solution is
选项：
A: As a solubilizer
B: To adjust the concentration of iodine
C: To reduce the irritation of iodine
D: As a hydrotropy agent
答案: 【 As a hydrotropy agent】
3、单选题：
Which of the following is not a common additive for liquid preparations
选项：
A: Oxidizing agent
B: Preservative
C: Flavoring agent
D: Antioxidant
答案: 【 Oxidizing agent】
Craft of Solid Preparations & Solid Preparations (1)
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6
6
6
6.5 Unit Operation of Solid Preparation——Drying
1、多选题：
Which are drying method below
选项：
A: Convection drying
B: Heat conduction drying
C: Radiation drying
D: Electric heating drying
答案: 【 Convection drying;
Heat conduction drying;
Radiation drying;
Electric heating drying】
2、判断题：
Increase air temperature or reduce air humidity can increase the constant speed drying.
选项：
A: 正确
B: 错误
答案: 【 正确】
7.1 Powders
1、单选题：
Which one is not the advantage of powder?
选项：
A: Have more better fluidity
B: Easy to disperse, rapid dissolution and rapid effect
C: Can simultaneously protect the wound and diminish swelling
D: The dosage is easy to control
答案: 【 Have more better fluidity】
2、判断题：
When the small dose of toxic drug mixing with several times the volume of diluents, we should use times mixing.
选项：
A: 正确
B: 错误
答案: 【 正确】
7.2 Granules
1、多选题：
Compared with powder, which are the features of granulation?
选项：
A: Less dust flying
B: Can prevent separation
C: Easy to storage and transportation
D: Can be coated to make enteric release
答案: 【 Less dust flying;
Can prevent separation;
Easy to storage and transportation;
Can be coated to make enteric release】
2、判断题：
Granules are made by mixing raw materials and appropriate excipients with a certain particle