大学MOOC Pharmacology(Wenzhou Medical University)1458031174 最新慕课完整章节测试答案

Quiz (Chapter 1 Introduction)

1、单选题：
‏Which is wrong about the description of the drug?‏
选项：
A: A chemical substance
B: A chemical that interferes with cellular metabolic activity
C: A substance that affects the physiological functions of the body
D: Has the nourishment, the nutrition, the health care, the rehabilitation function material
答案: 【 Has the nourishment, the nutrition, the health care, the rehabilitation function material】

2、单选题：
‎Pharmacology is an important subject in medical teaching because (     )‍
选项：
A: The mechanism of action of the drug was elucidated
B: Improve the quality of drugs, improve the efficacy of drugs
C: It provides experimental data and theoretical basis for the development of new drugs
D: It provides a theoretical basis for guiding rational drug use in clinical practice
答案: 【 It provides a theoretical basis for guiding rational drug use in clinical practice】

3、单选题：
‎The method of pharmacology is experimental means (     )‍
选项：
A: Strictly control the condition and observe the law and principle of drug action on the body
B: Using animals for experimental research
C: The drug was studied in vitro and in vivo
D: The experimental data provided have important reference value for clinic
答案: 【 Strictly control the condition and observe the law and principle of drug action on the body】

4、单选题：
​Pharmacodynamics is research (     )‏
选项：
A: Clinical efficacy of drugs
B: Ways to improve the efficacy of drugs
C: How to improve drug quality
D: Drug action on the body and the mechanism of action
答案: 【 Drug action on the body and the mechanism of action】

5、单选题：
​Pharmacokinetics is research (     )‍
选项：
A: Drug changes in the body and their regularity
B: How do drugs affect the body
C: A rational medication regimen
D: The dynamic changes of drugs and their laws
答案: 【 Drug changes in the body and their regularity】

6、单选题：
‍Pharmacology is research (   )‎
选项：
A: pharmacodynamics
B: pharmacokinetics
C: drug
D: Drug - body interaction and its law
答案: 【 Drug - body interaction and its law】

7、单选题：
‍New drugs must be provided (     ) for clinical trials‌
选项：
A: Systematic pharmacological research data
B: Acute and chronic toxicity were observed
C: LD50
D: Preclinical data
答案: 【 Preclinical data】

8、单选题：
‎The research object of pharmacology is‎
选项：
A: human body
B: body
C: Animal pathological model
D: healthy animal
答案: 【 body】

9、单选题：
‏The research object of experimental pharmacology is‏
选项：
A: animal
B: human body
C: body
D: health volunteer
答案: 【 animal】

10、单选题：
​The research object of clinical pharmacology is‎
选项：
A: human body
B: body
C: Animal pathological model
D: health volunteer
答案: 【 human body】

Quiz (Chapter 10 Sedative-Hypnotic)

1、单选题：
​The following description of benzodiazepam, which one is not correct ( )  ​
选项：
A: A. EnhancegabA's neurotransmitter function
B: B. Can be used as a pre-anaesthetic administration
C: C. Long-term non-addictive 
D: D. relaxant of central bone muscle pine
答案: 【 C. Long-term non-addictive 】

2、单选题：
‌The mechanism of central inhibition of benzodiazepine  is ( ) ​
选项：
A: Directly acting on the gamma-aminobutyric acid (GABA) receptor, opening the Cl-channel
B: Direct effect on benzodiazepine receptor, making Cl-channel open
C: Directly acting on benzodiazepine receptors, promoting CL-channel opening caused by GABA
D: Directly acting on GABA receptors, promoting Cl-channel opening due to benzodiazepine receptors
答案: 【 Directly acting on benzodiazepine receptors, promoting CL-channel opening caused by GABA】

3、单选题：
​The main reason for the clinical replacement of the traditional sedative hypnotic drug of the benzodiazepine class is ( )‏
选项：
A: The effect of benzodiazepine on fast wave sleep time is great   
B: Benzodiazepines can cause anesthesia
C: Small doses of benzodiazepines can produce hypnotic effects 
D: Benzodiazepines have better anti-anxiety and calming effects, good safety
答案: 【 Benzodiazepines have better anti-anxiety and calming effects, good safety】

4、单选题：
‍Enhanced GABA inhibition is due to the increase in the frequency of Cl-channel opening drugs is ( )‏
选项：
A: A. Benzodiazepines  
B: B. Barbitrates
C: C. Sodium Phentotoin     
D: D. cabamazepine
答案: 【 A. Benzodiazepines  】

5、单选题：
‎The narrative error of the adverse reaction of benzodiazepines is ( ) ‍
选项：
A: Overdose acute poisoning can cause coma and respiratory suppression
B: Large scope of safety, fewer serious consequences
C: Intravenous cardiovascular inhibition
D: Long-term service can produce dependence but is not addictive
答案: 【 Long-term service can produce dependence but is not addictive】

6、判断题：
‏When acute poisoning of phenylbarbital, in order to speed up its excretion from the kidneys, the measures to be taken is sodium bicarbonate solution‌‏‌
选项：
A: 正确
B: 错误
答案: 【 正确】

7、判断题：
‎The drug which has large safety range, breath suppression in the event of an overdose of acute poisoning is diazepam‍‎‍
选项：
A: 正确
B: 错误
答案: 【 正确】

8、判断题：
​diazepam has the effect of antidepression.‎
选项：
A: 正确
B: 错误
答案: 【 错误】

9、判断题：
‏In the case of acute poisoning of benzodiazepines, naloxone can be used.‌
选项：
A: 正确
B: 错误
答案: 【 错误】

10、判断题：
‎The process characteristics of benzodiazepines is good absorption of oral and muscle administration‎‎‎
选项：
A: 正确
B: 错误
答案: 【 错误】

Quiz (Chapter 11 Drugs for Psychiatric Disorders)

1、单选题：
‍Chlorpromazine can not be used for vomiting caused by ‎
选项：
A: A. Uremia
B: B. Cancer
C: C. Radiation sickness
D: D. Motion sickness
答案: 【 D. Motion sickness】

2、单选题：
​Which is the best answer to the effect of chlorpromazine on the receptor ()‌
选项：
A: Block DA, α, M receptors
B: Block dopamine receptors, block alpha receptors
C: Block dopamine receptors, block M receptors
D:  Block α receptor, block M receptor
答案: 【 Block DA, α, M receptors】

3、单选题：
‍Misrepresentation of the antipsychotic effect of chlorpromazine ‎
选项：
A: Has a strong neuroleptic effect
B: Can quickly control the patient's agitated symptoms
C: Ineffective for depression, even worse
D: Good curative effect on acute schizophrenia, with radical effect
答案: 【 Good curative effect on acute schizophrenia, with radical effect】

4、单选题：
‎The wrong statement about the anpyretic effect of chlorpromazine is () ​
选项：
A: Need to combine pethidine and promethazine
B: Inhibition of body temperature regulation center
C:  No effect on normal body temperature
D: Can reduce fever body temperature
答案: 【  No effect on normal body temperature】

5、单选题：
‍Lithium carbonate is mainly used for treatment () ​‍​
选项：
A: A. Anxiety
B: B. Schizophrenia
C: C. Mania
D: D. Parkinson's syndrome
答案: 【 C. Mania】

6、判断题：
‍Parkinson' s syndrome is not belong to Extrapyramidal reactions caused by chlorpromazine​
选项：
A: 正确
B: 错误
答案: 【 错误】

7、判断题：
​Antipsychotic effect: Chlorpromazine blocks D2 receptors in the midbrain-limb lobe and midbrain-cortex pathways ​​​
选项：
A: 正确
B: 错误
答案: 【 正确】

8、判断题：
‎Chlorpromazine blocks the substantia nigra-striatal pathway D2 receptor can cause extrapyramidal response‌
选项：
A: 正确
B: 错误
答案: 【 正确】

9、判断题：
‍ Chlorpromazine blocks M choline receptors can cause Dry mouth, constipation, blurred vision‎
选项：
A: 正确
B: 错误
答案: 【 正确】

10、判断题：
‌Chlorpromazine blocks the D2 receptor of CTZ  will cause Failure to regulate body temperature​
选项：
A: 正确
B: 错误
答案: 【 错误】

Quiz (Chapter 12 Epilepsy)

1、判断题：
‎The drug that is effective for major seizures, minor seizures, and psychomotor seizures is Phenobarbital‍‎‍
选项：
A: 正确
B: 错误
答案: 【 错误】

2、判断题：
‌The most effective treatment for small seizures and ineffective for other types of epilepsy is ethosuximide‏
选项：
A: 正确
B: 错误
答案: 【 正确】

3、判断题：
‌Grand-mal seizures are not part of the clinical use of phenytoin‍
选项：
A: 正确
B: 错误
答案: 【 错误】

4、判断题：
‍The first choice for major seizures or psychomotor seizures is carbamazepine‌
选项：
A: 正确
B: 错误
答案: 【 正确】

5、判断题：
‎The preferred drug for status epilepticus is diazepam‌
选项：
A: 正确
B: 错误
答案: 【 正确】

6、判断题：
‏Phenytoin sodium is a drug used to treat absent seizures‎
选项：
A: 正确
B: 错误
答案: 【 错误】

7、判断题：
‍Ataxia, nystagmus is not an adverse reaction of long-term use of phenytoin‏
选项：
A: 正确
B: 错误
答案: 【 错误】

8、判断题：
‏Carbamazepine, phenytoin and sodium valproate are effective for grand-mal seizure in epilepsy‌
选项：
A: 正确
B: 错误
答案: 【 正确】

9、判断题：
​The main clinical use of carbamazepine does not include bradyarrhythmia‎
选项：
A: 正确
B: 错误
答案: 【 正确】

10、判断题：
​Drugs with good efficacy for major seizures or localized seizures are phenytoin and carbamazepine​
选项：
A: 正确
B: 错误
答案: 【 正确】

Quiz (Chapter 13 Opioids)

1、判断题：
‏Morphine can be used for Bronchial asthma‍‏‍‏‍
选项：
A: 正确
B: 错误
答案: 【 错误】

2、判断题：
​Morphine acute poisoning can choose  Atropine to rescue‍​‍
选项：
A: 正确
B: 错误
答案: 【 错误】

3、判断题：
‌Compared with morphine, pethidine is more commonly used mainly due to stronger respiratory depression‍
选项：
A: 正确
B: 错误
答案: 【 错误】

4、判断题：
‏The reason why pethidine is not used alone to treat biliary colic due to  it can cause biliary sphincter spasm‌
选项：
A: 正确
B: 错误
答案: 【 正确】

5、判断题：
​The analgesic effect of morphine is most suitable for the diagnosis of unexplained acute abdominal pain‌
选项：
A: 正确
B: 错误
答案: 【 错误】

6、判断题：
‎For Bile colic, atropine + pethidine is best used‌
选项：
A: 正确
B: 错误
答案: 【 正确】

7、判断题：
‏Morphine has stronger analgesic effect than dulending‌
选项：
A: 正确
B: 错误
答案: 【 正确】

8、判断题：
‍Morphine is more addictive than dulending​
选项：
A: 正确
B: 错误
答案: 【 正确】

9、判断题：
‎Pethedine and morphine both have strong antitussive effects‏
选项：
A: 正确
B: 错误
答案: 【 错误】

10、判断题：
​Women's delivery is not a contraindication for morphine‌
选项：
A: 正确
B: 错误
答案: 【 错误】

Quiz (Chapter 14 Nonsteroid Anti- Inflammatory Drugs)

1、判断题：
​The main site and mechanism of aspirin's analgesic effect is the synthesis of PG when preventing inflammation in the periphery‏
选项：
A: 正确
B: 错误
答案: 【 正确】

2、判断题：
‏The drug without anti-inflammatory and anti-rheumatic effect is acetaminophen‎
选项：
A: 正确
B: 错误
答案: 【 正确】

3、判断题：
‏Aspirin prevents thrombosis by inhibiting cyclooxygenase activity and reducing TXA2 production in platelets‌
选项：
A: 正确
B: 错误
答案: 【 正确】

4、判断题：
‎Aspirin salicylic acid reaction can be rescued with potassium chloride‏
选项：
A: 正确
B: 错误
答案: 【 错误】

5、判断题：
‏The principle of aspirin's antipyretic effect is to inhibit prostaglandin synthesis​
选项：
A: 正确
B: 错误
答案: 【 正确】

6、判断题：
​Gastrointestinal reaction is a common adverse reaction for aspirin​
选项：
A: 正确
B: 错误
答案: 【 正确】

7、判断题：
‌Aspirin is effective against bacterial inflammation‏
选项：
A: 正确
B: 错误
答案: 【 错误】

8、判断题：
‏Excessive acetaminophen can cause liver necrosis‏
选项：
A: 正确
B: 错误
答案: 【 正确】

9、判断题：
‎Common adverse reactions of aspirin include gastrointestinal reactions and arrhythmias‎
选项：
A: 正确
B: 错误
答案: 【 错误】

10、判断题：
‌Aspirin is contraindicated in bronchial asthma‌
选项：
A: 正确
B: 错误
答案: 【 正确】

Quiz (Chapter 15 Drugs Used in Angina Pectoris)

1、单选题：
‌The principle of cardiac toxicity caused by cardiac glycoside is ​
选项：
A: increase K+
B:  in cardiomyocytes, increase Ca2+ in cardiomyocytes
C: Excite Na+-K+-ATPase of myocardial cell membrane
D:  Inhibit Na+-K+-ATPase of myocardial cell membrane
答案: 【  Inhibit Na+-K+-ATPase of myocardial cell membrane】

2、单选题：
‍Captopril will lead to (    )‎‍‎‍‎
选项：
A: Elevated blood potassium 
B: Gum hyperplasia
C:  Anaphylactic shock
D: Reflex heart rate rise
答案: 【 Elevated blood potassium 】

3、单选题：
‍The common effect of nitroglycerin, β-blocker and calcium antagonist on angina pectoris is‏
选项：
A: Dilate blood vessels
B: Inhibit myocardial contractility
C: Reduce myocardial oxygen consumption
D: Slow down heart rate
答案: 【 Reduce myocardial oxygen consumption】

4、单选题：
‍Which of the following adverse reactions is not related to the role of nitroglycerin in dilating blood vessels ‏‍‏
选项：
A: Increased heart rate
B: Orthostatic hypotension
C: Elevated intraocular pressure 
D: Meteorhemoglobinemia
答案: 【 Meteorhemoglobinemia】

5、单选题：
‍It is best to choose atrioventricular block or sinus bradycardia caused by cardiac glycoside poisoning‎‍‎
选项：
A: aminophylline 
B:  phenytoin 
C:  atropine
D:  isoproterenol
答案: 【  atropine】

6、单选题：
‌The drug that exerts antihypertensive effect by inhibiting angiotensin converting enzyme is‍‌‍
选项：
A: Clonidine
B:  Enalapril (Phenyl Proline)
C: Reserpine
D: Sodium nitroprusside
答案: 【  Enalapril (Phenyl Proline)】

7、判断题：
​Captopril combined with potassium-retaining diuretics, it is easy to cause hyperkalemia‍
选项：
A: 正确
B: 错误
答案: 【 正确】

8、判断题：
​For patients with stable angina, you should choose nitroglycerin. ‎
选项：
A: 正确
B: 错误
答案: 【 正确】

9、判断题：
‌When digoxin is used for CHF treatment， it can reduce blood volume and reduce heart load ‏
选项：
A: 正确
B: 错误
答案: 【 错误】

10、判断题：
‌Beta blockers can increase myocardial contractility and increase cardiac output to give treatment for heart failure.‎
选项：
A: 正确
B: 错误
答案: 【 错误】

Quiz (Chapter 16 Antihypertensive)

1、单选题：
​Which medicine does not increase the heart rate when dilating blood vessels to lower blood pressure(  )‎
选项：
A: Hydralazine
B: Phentolamine
C: Nitroglycerin
D: Labello
答案: 【 Labello】

2、单选题：
​For hypertension with peptic ulcers, the preferred antihypertensive drug is (   )‎
选项：
A: Prazosin
B: Methyldopa
C: Nifedipine
D: Clonidine
答案: 【 Clonidine】

3、单选题：
‌Angiotensin Ⅰ converting enzyme inhibitor is () ‍
选项：
A: Sodium nitroprusside
B: Captopril
C: Hydralazine Pyridazine
D: Prazosin
答案: 【 Captopril】

4、单选题：
‎The drug that reduces blood pressure by directly blocking the α1 receptor is(   )‌
选项：
A: Risaping
B: Methyldopa
C: Prazosin
D: Nifedipine
答案: 【 Prazosin】

5、单选题：
‎The central antihypertensive drug is (    ) ‎
选项：
A: Clonidine
B: Risaping
C: Labellol
D: Hydralazine
答案: 【 Clonidine】

6、单选题：
‍The drug that exerts an antihypertensive effect by blocking α1 and β receptors is (  )‍
选项：
A: Prazosin
B: Propranolol
C: Nifedipine
D: Labello
答案: 【 Labello】

7、单选题：
​The medicine that lowers blood pressure by affecting the renin-angiotensin-aldosterone system is (   )​
选项：
A: Risaping
B: Prazosin
C: Methyldopa
D: Captopril
答案: 【 Captopril】

8、单选题：
‏Which drug should not be used for hypertension with heart failure ()‎
选项：
A: Propranolol 
B: Captopril
C: Prazosin
D: Hydrochlorothiazide
答案: 【 Propranolol 】

9、单选题：
‍The strongest antihypertensive effect is () ‎
选项：
A: α-Methyldopa
B: Clonidine
C: Guanfasin
D: Moxonidine
答案: 【 Clonidine】

10、单选题：
‎Which of the following antihypertensive drugs is likely to cause the "first dose phenomenon" ()​
选项：
A: Hydrochlorothiazide
B: Captopril
C: Prazosin
D: Propranolol
答案: 【 Prazosin】

Quiz (Chapter 17 Basic Pharmacology of Drugs Used in Heart Failure)

1、单选题：
‏Which of the following cardiac glycosides is most completely absorbed after oral administration‌
选项：
A: digitalis glycoside
B: digoxin
C:  flavoside
D: genin C
答案: 【 digitalis glycoside】

2、单选题：
‏Which of the following drugs can increase the blood concentration of digoxin ‎
选项：
A: KCl
B: spironolactone
C: cholestyramine
D: quinidine
答案: 【 quinidine】

3、单选题：
‏The most common early symptom of cardiac glycoside poisoning is‌
选项：
A: ECG has a shortened Q-T interval
B: headache
C: gastrointestinal reaction
D: atrioventricular block
答案: 【 gastrointestinal reaction】

4、单选题：
‍Sinus bradycardia caused by cardiac glycoside poisoning can be used(  )‏
选项：
A: potassium chloride
B: atropine
C: lidocaine
D: epinephrine
答案: 【 atropine】

5、单选题：
‍The following drugs are not suitable for the treatment of heart failure‍
选项：
A: adrenaline
B: nitroglycerin
C: hydrochlorothiazide
D: prazosin
答案: 【 adrenaline】

6、单选题：
‏ The principle of cardiac toxicity caused by cardiac glycoside is (   )‏
选项：
A: Inhibit Na+-K+-ATPase of myocardial cell membrane 
B: Excite Na+-K+-ATPase of myocardial cell membrane
C: Increase K+ in cardiomyocytes
D: Increase Ca2+ in cardiomyocytes
答案: 【 Inhibit Na+-K+-ATPase of myocardial cell membrane 】

7、单选题：
‌Which of the following drugs is banned from cardiogenic asthma (   )‌
选项：
A: morphine
B: sildilan 
C: epinephrine
D: aminophylline
答案: 【 epinephrine】

8、单选题：
​ The reason why cardiac glycoside slows the ventricular rate in patients with atrial fibrillation is (  )‌
选项：
A: Decrease the autonomy of atrial muscles
B: Decrease the autonomy of ventricular muscles
C: Improve myocardial ischemia
D: Increase the occult conduction in the atrioventricular node
答案: 【 Increase the occult conduction in the atrioventricular node】

9、单选题：
‎Cardiac glycoside is better for heart failure caused by which of the following diseases (    )‍
选项：
A: high blood pressure
B: severe anemia
C: hyperthyroidism
D: VB1 deficiency
答案: 【 high blood pressure】

10、单选题：
‍Cardiac glycosides are prohibit used in (   )‎
选项：
A: Heart failure caused by hypertension
B: Atrial fibrillation
C: supraventricular tachycardia
D: ventricular tachycardia
答案: 【 ventricular tachycardia】

Quiz (Chapter 18 Agents Used in Cardiac Arrhythmias)

1、单选题：
‌Which of the following anti-arrhythmias agents can  block cacium channel ?​
选项：
A: verapamil
B: procaine
C: lidocaine
D: quinidine
E: flecainide
答案: 【 verapamil】

2、单选题：
​Which of the following agents can be used in ventricular tachyarrhythmia caused by acute myocardial infarction.‌​‌
选项：
A: lidocaine
B: quinidine
C: propranolol
D: verapamil
E: amiodarone
答案: 【 lidocaine】

3、单选题：
‍suppression of arrhythmias resulting from a reentry focus is most like