1-Introduction of Immunology

Test of Introduction

1、单选题:
Immunologic homeostatic abnormality may result in ‍
选项:
A: immunologic deficiency disease
B: Hypersensitivity
C: autoimmune disease  
D: tumorigenesis
E: viral persistence infection
答案: 【 autoimmune disease  

2、单选题:
​The immunologic defense abnormality may result in ‌
选项:
A: immunologic deficiency disease 
B: autoimmune disease 
C: Tumorigenesis
D: Hypersensitivity
答案: 【 Hypersensitivity

3、单选题:
‌The definition of immunity is‌‌‌
选项:
A: To eliminate pathogenic microorganism
B: to eliminate damaged or dead cells and mutant malignant or tumor cells
C: Immunity is the function of an individual distinguishes “self” from “non-self”,and excludes antigenic foreign substances.
D: protect our body from certain diseases, particularly infectious diseases and tumor.
答案: 【 Immunity is the function of an individual distinguishes “self” from “non-self”,and excludes antigenic foreign substances.

4、单选题:
‍Which one is the central immune organ of human​
选项:
A: lymph node
B: Spleen;
C: Bone marrow;
D: Tonsil
答案: 【 Bone marrow;

5、单选题:
‏Which one is the biggest peripheral immune organs of human‎
选项:
A:  lymph node;
B: Spleen;
C: Bone marrow;
D: Tonsil;
答案: 【 Spleen;

6、单选题:
‍Who invented the cowpox vaccine against small pox ‏
选项:
A: Edward Jenner;
B:  Koch;
C: Pasteur
D: Burnet; 
答案: 【 Edward Jenner;

10.Immune cellT lymphocyte

Test of T lymphocyte

1、单选题:
‎T cells are made in the____ and complete their differentiation in the____.‎
选项:
A: Spleen; Thyroid
B: Spleen; Thymus
C: Bone marrow; Thymus
D: Bone marrow; Bone marrow; 
答案: 【 Bone marrow; Thymus

2、单选题:
‏Which cell has the ability to produce immune memory ?‍
选项:
A: Macrophages
B: Neutrophil
C: Natural Killer (NK) 
D: T cell
答案: 【 T cell

3、单选题:
T helper (Th) lymphocytes are characterized by (      )‍
选项:
A: Expression of membrane IgM/IgD on the cell membrane;
B: Expression of CD4 on cell membrane; 
C: Secretion of immunoglobulins;
D: Cytotoxic activity;
答案: 【 Expression of CD4 on cell membrane; 

4、单选题:
T cells membrane molecules NOT include (     )‎
选项:
A: CD3
B: CD4
C: CD8
D: CD40
答案: 【 CD40

5、单选题:
‍CD8 is a co-receptor on T cells that binds (         )‏
选项:
A: CD3
B: endogenous antigen peptide
C: α3 region of Class I MHC molecule
D: constant region of TCR
答案: 【 α3 region of Class I MHC molecule

11. Ag presenting Cell (APC)

Test of APC

1、单选题:
‍Which cell could present Ag to naïve T cell, initiate primary immune response‌
选项:
A: DC
B: NK cells
C: macrophage
D: B cell
答案: 【 DC

2、单选题:
‌lipid-antigen could be present by (      ) pathway‏
选项:
A: CD1
B: CD2
C: MHC class I
D: MHC class II
答案: 【 CD1

3、单选题:
‎Assembly of antigenic peptide-class I MHC complex occurs in (      )‎
选项:
A: Cytosol;
B: Endoplasmic reticulum(ER)
C: Golgi complex
D:  lysosomes
答案: 【 Endoplasmic reticulum(ER)

4、单选题:
The component involved in MHC class I pathway of antigen processing is (      )‌
选项:
A: LMP
B: Ii chain
C: HLA-DR
D: HLA-DQ
答案: 【 LMP

5、单选题:
Extracellular antigen degraded takes place in (     )‏
选项:
A: Proteasomes
B: Endoplasmic reticulum (ER)
C: Golgi complex
D: lysosome
答案: 【 lysosome

12. T cells mediated Adaptive response

Test of T cells mediated Adaptive response

1、单选题:
Antigen-specific effector of Cellular immunity is (      )‍
选项:
A: antibodies;
B: B cells;
C: cytokines;
D: E. Th1 cells
答案: 【 E. Th1 cells

2、单选题:
‎which of the following is MHC restricted? ‌
选项:
A: CTL and target cell;
B:

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