Chapter 1 An overview of Immunology

Chapter 1 Unit test

1、单选题:
‏The earliest method to prevent smallpox invented by Chinese folk doctors is (      ).​
选项:
A: Inoculate cowpox vaccine
B: Inoculate smallpox scab powder 
C: Inoculate smallpox vaccine
D: Inoculate Hepatitis B vaccine 
答案: 【 Inoculate smallpox scab powder 

2、单选题:
‏The inventor of the cowpox vaccine is (      ).​
选项:
A: France's Pasteur
B: Germany's Koch   
C: Australia's Burnet    
D: England's Jenner 
答案: 【 England's Jenner 

3、单选题:
‍The first antibody found in the world is (      ).​
选项:
A: diphtheria antitoxin
B: tetanus antitoxin
C: rabies vaccine
D: hepatitis B vaccine
答案: 【 diphtheria antitoxin

4、单选题:
‌For the exploration of the mechanism of antibody production, the one accepted generally is (      ).‏
选项:
A: Template Theory 
B: Indirect Template Theory
C: Natural Selection Theory
D: Clonal Selection Theory
答案: 【 Clonal Selection Theory

5、单选题:
‌About 17:30 on October 1, 2018, Beijing time, American immunologist James P. Allison and Japanese immunologist Tasuku Honjo were awarded the 2018 Nobel Prize in physiology or medicine for their outstanding contributions in the field of (       ).‍
选项:
A: treatment of infectious diseases
B: tumor immunity
C: immunoserotherapy 
D: antibody diversity mechanism
答案: 【 tumor immunity

6、多选题:
‍The three functions of the immune system are (       ).‍
选项:
A: immunological defense 
B: immune homeostasis
C: Immunosurveillance
D: immunological tolerance
答案: 【 immunological defense ;
immune homeostasis;
Immunosurveillance

7、多选题:
‏The function of immunological defense refers to (       ).‏
选项:
A: prevent pathogenic microorganisms invading the body
B: inhibit the proliferation and spread of pathogenic microorganisms in the body
C: clear the old, dead, or damaged cells in the body
D: remove pathogenic microorganisms and their products from the body
答案: 【 prevent pathogenic microorganisms invading the body;
inhibit the proliferation and spread of pathogenic microorganisms in the body;
remove pathogenic microorganisms and their products from the body

8、多选题:
​Factors contributing to the rise of scientific immunology include (       ).‏
选项:
A: Antoni van Leeuwenhoek improved the microscope which promotes the isolation and identification of pathogenic bacteria
B: Pastuer identified that bacillus anthrax cultured in Lab can cause disease in animals
C: Koch put forward the concept of pathogenic bacteria
D: Jenner invented the cowpox vaccine
答案: 【 Antoni van Leeuwenhoek improved the microscope which promotes the isolation and identification of pathogenic bacteria;
Pastuer identified that bacillus anthrax cultured in Lab can cause disease in animals;
Koch put forward the concept of pathogenic bacteria

9、判断题:
‏When the function of immune homeostasis is low, the body is prone to various neoplastic diseases.‌
选项:
A: 正确
B: 错误
答案: 【 错误

10、判断题:
‎Immunity and infection are conflicting. In general, infection can elicit immunity and the induced immunity can terminate the infection.‌
选项:
A: 正确
B: 错误
答案: 【 正确

11、判断题:
‍People's understanding of immunity started from infectious diseases and anti-infection immunity.​
选项:
A: 正确
B: 错误
答案: 【 正确

12、判断题:
‌In 1979, the World Health Organization (WHO) solemnly declared in Nairobi, Kenya, that “poliomyelitis” had been eradicated all over the world.​
选项:
A: 正确
B: 错误
答案: 【 错误

Chapter 11-2 Hypersensitivity

Chpater 11 Unit test

1、单选题:
‏Of the four types of hypersensitivity, type I hypersensitivity is also known as (     ) because it occurs most quickly after reexposure to an antigen. ‌
选项:
A: immediate hypersensitivity
B: cytotoxic hypersensitivity
C: immune complex hypersensitivity
D: delayed-type hypersensitivity
答案: 【 immediate hypersensitivity

2、单选题:
‎Among the following diseases, which one is type II hypersensitive disease?  (      )‍
选项:
A: hemolytic disease of the newborn
B: contact dermatitis
C: penicillin anaphylactic shock
D: systemic lupus erythematosus
答案: 【 hemolytic disease of the newborn

3、单选题:
‏Type I hypersensitivity can be passively transferred by which components of the patients.(    )‎
选项:
A: sensitized lymphocyte
B: serum
C: transfer factor
D: chemokine
答案: 【 serum

4、单选题:
‏Which of the following diseases is immune complex disease? (      )‌
选项:
A: hyperthyroidism
B: urticaria
C: hemolytic disease of the newborn
D: systemic lupus erythematosus
答案: 【 systemic lupus erythematosus

5、单选题:
​Drugs or chemical allergens causing type I hypersensitivity are mainly hapten. After entering the body and combining with some proteins or cells, they become complete antigen and then acquire immunogenicity, inducing the body to produce specific (      ) antibody which make the body in a state of sensitization by combining with high-affinity receptor on the surface of mast cells or basophils through the Fc before binding with antigens.‍
选项:
A: IgA
B: IgG
C: IgE
D: IgM
答案: 【 IgE

6、多选题:
​The mechanisms of desensitization therapy for type I hypersensitivity diseases involve many aspects, including (     ).‍
选项:
A: desensitizing the sensitized cells in batches
B: the blocking action of IgG
C: regulating Th1/Th2 cells by allergens
D: the regulatory role of Treg cells
E: reducing IgE response
答案: 【 desensitizing the sensitized cells in batches;
the blocking action of IgG;
regulating Th1/Th2 cells by allergens;
the regulatory role of Treg cells;
reducing IgE response

7、多选题:
‍The bioactive substances that mediate type I hypersensitivity are mainly released by  (      ).‌
选项:
A: macrophages
B: monocytes
C: mast cells
D: basophils
答案: 【 mast cells;
basophils

8、多选题:
‍When what factors occur, the body may develop rheumatoid arthritis (RA)? (      )‍
选项:
A: A large number of IgE are produced.
B: neutrophil infiltration
C: platelet activation
D: Th1 cell activation
E: A medium-sized soluble antigen-antibody complex is formed.
答案: 【 neutrophil infiltration;
platelet activation;
A medium-sized soluble antigen-antibody complex is formed.

9、多选题:
‏Which of the following substances can cause type I hypersensitivity? (      )‏
选项:
A: animal dander
B: penicillin
C: house dust
D: milk
E: pollen
答案: 【 animal dander;
penicillin;
house dust;
milk;
pollen

10、判断题:
‍Type I hypersensitivity has obvious individual differences and heritability.‎
选项:
A: 正确
B: 错误
答案: 【 错误

11、判断题:
​The antibodies that cause the hypersensitivity are called allergins.‌
选项:
A: 正确
B: 错误
答案: 【 错误

12、判断题:
‍The tuberculin test is a typical example of infectious delayed-type hypersensitivity.‍
选项:
A: 正确
B: 错误
答案: 【 正确

13、判断题:
‌Allergic diseases are becoming more and more common in People's Daily life and have become a global health problem.‏
选项:
A: 正确
B: 错误
答案: 【 正确

14、判断题:
‏Both hypersensitivity and adaptive immune responses are essentially specific immune responses to certain antigens, but hypersensitivity focuses on tissue damage and/or physiological disorders caused by this process.‏
选项:
A: 正确
B: 错误
答案: 【 正确

Chapter 12 The immune prevention

Chapter 12 Unit test

1、单选题:
‎Immunoprophylaxis adopts the principle of (      ).‏
选项:
A: acquired immune response
B: innate immune response
C: natural immune response
D: immunological tolerance
答案: 【 acquired immune response

2、单选题:
‏Turkey herpes virus vaccine can be used to prevent Marek's disease of chickens because chicken Marek's virus and Turkey herpes virus share a common (      ).‎
选项:
A: protective antigen
B: genome structure
C: capsule protein
D: nuclear protein
答案: 【 protective antigen

3、单选题:
​Which one of the following is one of the purposes of developing a tumor vaccine by modifying the genetic characters of tumor cells (      )?‏
选项:
A: eliminating tumorigenicity 
B: enhancing immunogenicity
C: enhancing antigenicity
D:  reducing reactogenicity
答案: 【 enhancing immunogenicity

4、单选题:
‎The vaccine made by conjugating the bacterial capsular polysaccharide to a protein carrier is called (     ).‌
选项:
A: conjugate vaccine
B: multivalent vaccine
C: combination vaccine
D: therapeutic vaccine
答案: 【 conjugate vaccine

5、单选题:
‏In addition to injection, aerosol, etc., drinking water, oral, nasal or eye drops may be used for animal vaccine immunization, but these immunization routes are mainly suitable for some (     ) vaccines.​
选项:
A: inactivated
B: live
C: nucleic acid
D: therapeutic
答案: 【 live

6、多选题:
‏Thanks to vaccination and other prevention and control measures, animal diseases eliminated in China include (      ).​
选项:
A: rinderpest 
B: contagious bovine pleuropneumonia 
C: equine infectious anemia
D: classical swine fever
答案: 【 rinderpest ;
contagious bovine pleuropneumonia 

7、多选题:
​Immunoprophylactic preparations include (      ).‎
选项:
A: vaccine
B: toxoid
C: antitoxin
D: monoclonal antibody
E: immune serum
答案: 【 vaccine;
toxoid;
antitoxin;
monoclonal antibody;
immune serum

8、多选题:
‏Requirements for an ideal vaccine include (      ).‎
选项:
A: safe
B: effective
C: practical
D: stable and easy to preserve
E: easy to manufacture and inexpensive
答案: 【 safe;
effective;
practical;
stable and easy to preserve;
easy to manufacture and inexpensive

9、判断题:
‌The maternal antibody has no interference effect on the attenuated vaccine.‌
选项:
A: 正确
B: 错误
答案: 【 错误

10、判断题:
‏Allergic reactions should be considered when using antiserums for emergency prevention of diseases.‍
选项:
A: 正确
B: 错误
答案: 【 正确

11、判断题:
‌Artificial active immunization is mainly used for disease prevention, while artificial passive immunization is mainly used for treatment and emergency prevention of diseases.‏
选项:
A: 正确
B: 错误
答案: 【 正确

12、判断题:
‏When selecting a vaccine for the prevention of a certain infectious disease in a certain area, it is necessary to consider the consistency between the vaccine type and the local pathogen type.‌
选项:
A: 正确
B: 错误
答案: 【 正确

13、判断题:
‌In terms of immunological methods, injection immunization is time-consuming and laborious in veterinary practice, but it applies to almost all vaccines and is effective; while aerosol immunization is convenient and suitable for mass immunization, but it requires proprietary equipment and has the risk of inducing respiratory diseases.‏
选项:
A: 正确
B: 错误
答案: 【 正确

Chapter 2 Immune Organs and Tissues

Chapter 2 Unit test

1、单选题:
​Compared with normal mice, mice immunized with antigens for many times have the larger and heavier spleens because of (      ).‎
选项:
A: proliferation of antigen specific T cells
B: proliferation of antigen specific B cells
C: proliferation of antigen specific T and B cells
D: proliferation of antigen non-specific T and B cells
答案: 【 proliferation of antigen specific T and B cells

2、单选题:
‏B cells of humans and mammals mature in (      ).‌
选项:
A: thymus
B: bone marrow 
C: bursa of Fabricius
D: tonsil
答案: 【 bone marrow 

3、单选题:
‎(       ) is the s

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